wt1 proteins การใช้

The scientists used sensitive laboratory tests to determine whether breast cells were producing WT1 protein as they should.
The WT1 protein has been found to bind a host of cellular factors, e . g . p53, a known tumor suppressor.
This could mean, Roberts said, that the gene's blueprint is intact but that blueprint isn't correctly translated into the WT1 protein by the cell.
In normal cells, the WT1 protein was detected, but it was absent in epithelial cells _ those that line the milk ducts of the breast, where tumors begin.
If this defect is truly a cause of cells becoming malignant, it could be possible to supply the WT1 protein to those cells, said Roberts, though this is entirely speculation.